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Aim&Scope:  Signal Transduction and Targeted Therapy is an international, peer-reviewed, open-access journal that publishes original research articles and review articles related to all aspects of signal transduction in physiological and pathological processes, as well as signal transduction-targeted therapeutics in the form of biological agents and small molecular drugs used to treat human diseases such as cancer, autoimmune disorders, and others. This journal focuses on cutting-edge advances both experimentally and clinically.